Circulating, cell-free methylated DNA indicates cellular sources of allograft injury after liver transplant
Megan E. McNamara, Sidharth S Jain, Kesha Oza, Vinona Muralidaran, Amber J. Kiliti, A. Patrick McDeed, Digvijay Patil, Yuki Cui, Marcel O. Schmidt, Anna Tate Riegel, Alexander Kroemer, Anton Wellstein
The paper uses cfDNA methylation patterns to detect allograft injury after liver transplants and identifies early-onset injury through sustained cfDNA elevation.
Nature Communications · Jun 17, 2025Peer-reviewedMolecular Biology