A dynamic microRNA profile that tracks a chemotherapy resistance phenotype in osteosarcoma. Implications for novel therapeutics.
Christopher E. Lietz, Erik T. Newman, Andrew D. Kelly, David Haosen Xiang, Ziying Zhang, Nikhil Ramavenkat, Joshua J. Bowers, Santiago A. Lozano‐Calderón, David H. Ebb, Kevin A. Raskin, Gregory Michael Cote, Edwin Choy, G. Petur Nielsen, Ioannis S. Vlachos, Benjamin Haibe‐Kains, Dimitrios Spentzos
The paper identifies a dynamic microRNA profile associated with chemotherapy resistance in osteosarcoma and predicts novel therapeutic targets that could reverse resistance.
medRxiv · Jun 19, 2024 · PreprintGenetic & Genomic Medicine