Author

Kevin R Brown

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Systems Biology· 1

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Approach:Bayesian inference· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Organism:human· 1

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Fabrice Sircoulomb· 1 shared Jason MoffatiD· 1 shared Robert Rottapel· 1 shared Traver HartiD· 1 shared

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2014-2014 · peak 1/yr

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1 shared paperSystems Biology

Fabrice Sircoulomb

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1 paper

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Systems BiologybioRxivMar 17, 2014

Measuring error rates in genomic perturbation screens: gold standards for human functional genomics

Traver Hart, Kevin R Brown, Fabrice Sircoulomb…·Jason Moffat

This paper develops a Bayesian classifier to improve gene essentiality analysis in genomic perturbation screens and shows CRISPR is more sensitive than RNAi with manageable false discovery rates.

DOI 10.15252/msb.20145216

humanCRISPR screen