Machine-learning based detection of adventitious microbes in T-cell therapy cultures using long read sequencing
James P. B. Strutt, Meenubharathi Natarajan, Elizabeth Lee, Denise Bei Lin Teo, Wei‐Xiang Sin, Ka-Wai Cheung, Marvin Chew, Khaing Thazin, Paul W. Barone, Jacqueline M. Wolfrum, Rohan B. H. Williams, Scott A. Rice, Stacy L. Springs
This paper develops a machine learning approach using long-read sequencing to rapidly detect microbial contaminants in T-cell therapy cultures at low abundance.
Microbiology Spectrum · Aug 30, 2023Peer-reviewedBioinformatics