Mechanochemical Decoupling of ATP Hydrolysis and RNA Translocation in SARS-CoV-2 nsp13 by the L405D Mutation
Elham Fazelpour, Priti Roy, Kole Frederick, Martin McCullagh
This paper investigates how the L405D mutation in SARS-CoV-2 nsp13 decouples ATP hydrolysis from RNA translocation by altering conformational dynamics.
The Journal of Physical Chemistry B · Sep 9, 2026Peer-reviewedBiophysics