A large-scale transcriptome-wide association study (TWAS) of ten blood cell phenotypes reveals complexities of TWAS fine-mapping
Amanda L. Tapia, Bryce Rowland, Jonathan D. Rosen, Michael H Preuss, Kris Young, Mariaelisa Graff, Hélène Choquet, David J. Couper, Steven G. Buyske, Stephanie A. Bien, Eric Jorgenson, Charles L Kooperberg, Ruth J. F. Loos, Alanna C. Morrison, Kari E. North, , Laura M. Raffield
This paper performs a large-scale TWAS of blood cell phenotypes, identifies 239 gene-trait associations, and develops an R Shiny app to visualize TWAS results.
bioRxiv · Feb 23, 2021 · PreprintGenetics