Mathematical Models for the Influence of Cytarabine on White Blood Cell Dynamics in Acute Myeloid Leukemia
Felix Jost, Enrico Schalk, Kristine Rinke, Thomas Fischer, Sebastian Säger
The paper develops and evaluates mathematical models to predict white blood cell dynamics during cytarabine treatment in AML, finding that different models yield similar accuracy and identifying a new pharmacodynamic hypothesis.
bioRxiv · Sep 27, 2018 · PreprintSystems Biology