Differential Associations of Interleukin 6 Receptor Variant Across Genetic Ancestries and Implications for Targeted Therapies
Xuan Wang, Isabelle-Emmanuella Nogues, Molei Liu, Tony Chen, Xin Xiong, Clara-Lea Bonzel, Harrison G. Zhang, Chuan Hong, Kumar P. Dahal, Lauren Costa, J. Michael Gaziano, Seoyoung C. Kim, Yuk-Lam Anne Ho, Kelly Cho, Tianxi Cai, Katherine P. Liao
The paper examines differential associations of the IL6R variant across genetic ancestries and identifies trait differences that may inform targeted therapies.
medRxiv · Sep 24, 2022 · PreprintGenetic & Genomic Medicine