Differential genomic and transcriptomic events associated with high-grade transformation of Chronic Lymphocytic Leukemia
Jenny Klintman, Basile Stamatopoulos, Kate E. Ridout, Toby Andrew Eyre, L. Lopez Pascua, Niamh Appleby, Samantha J.L. Knight, Helene Marie-Pierre Dreau, Mats Ehinger, José Ignacio Martín-Subero, Elı́as Campo, Robert Månsson, Davide Rossi, Jenny C. Taylor, Dimitris V. Vavoulis, Anna Schuh
The paper identifies genomic and transcriptomic changes in CLL transforming to RS, finding pathway mutations and non-coding mutations in PAX5 enhancers associated with transformation.
HemaSphere · Jun 1, 2019Peer-reviewedGenomics