Deciphering the mechanism of inhibition of SERCA1a by sarcolipin using molecular simulations
L. Mouawad, V. Beswick, N. Jamin, C. Montigny, E. Quiniou, T. Barbot
This paper uses molecular simulations to investigate how sarcolipin inhibits SERCA1a by altering its structure and function, revealing a mechanism that affects Ca2+ transport and conformational transitions.
bioRxiv · Dec 17, 2019Biophysics