Molecular changes during extended neoadjuvant letrozole treatment of breast cancer: distinguishing acquired resistance from dormant tumours
C. Selli, A. K. Turnbull, D. A. Pearce, A. Li, A. Fernando, J. Wills, L. Renshaw, J. S. Thomas, J. M. Dixon, A. H. Sims
This study compares molecular changes in dormant and acquired resistant breast cancer tumors during extended letrozole treatment, finding distinct epigenetic alterations in resistant tumors.
bioRxiv · Sep 25, 2018Cancer Biology