Morphological profiling of human T and NK lymphocytes identifies actin-mediated control of the immunological synapse
Y. German, L. Vulliard, A. Rubio, K. Boztug, A. Ferrand, J. Menche, L. Dupre
This study uses morphological profiling to identify actin-mediated control of the immunological synapse in human T and NK lymphocytes, revealing inter-individual heterogeneity and defects in ARPC1B-mutated CD8+ T cells.
bioRxiv · Jan 17, 2020 · PreprintImmunology