Unraveling the heterogeneous mutational signature of spontaneously developing tumors in MLH1-/- mice
Y. Gladbach, L. Wiegele, M. Hamed, A. M. Merkenschläger, G. Fuellen, C. Junghanss, C. Maletzki
This study identifies heterogeneous mutational signatures in MLH1-/- mouse tumors, revealing shared and exclusive mutations and their implications for tumor development and immunotherapy.
bioRxiv · Aug 5, 2019Cancer Biology