HDAC6 is a novel regulator of endothelial-to-mesenchymal transition in venous thrombosis
Marion Pilard, Virginie Gourdou‐Latyszenok, Lénaïck Gourhant, Estelle L. Ollivier, Thibaut Riou, Jamal Elhasnaoui, Lanig Civi, Lena Bicrel, Rafael Ricci de Azevedo, Sara Robin, Gilles Pernod, Cécile Tromeur, Françis Couturaud, Catherine A. Lemarié
This study identifies HDAC6 as a regulator of endothelial-to-mesenchymal transition (EndMT) in venous thrombosis, showing that inhibiting HDAC6 reduces thrombus size and EndMT markers.
bioRxiv · Sep 1, 2026 · PreprintPhysiology