Author

Laura A. Sena

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Angelo Michael De MarzoiD· 1 shared Emmanuel S. Antonarakis· 1 shared Jiaying LaiiD· 1 shared Laura DeLong WoodiD· 1 shared Mark C. Markowski· 1 shared Rachel KarchiniD· 1 shared Srinivasan YegnasubramanianiD· 1 shared Yi Yang· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Angelo Michael De MarzoORCID

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1 paper

Recent·Most cited

Longitudinal structural variant phylogenies define tumor evolution under therapeutic selection pressure in metastatic prostate cancer

YunZhou Liu, Jiaying Lai, Yi Yang, Mark C. Markowski, Emmanuel S. Antonarakis, Angelo Michael De Marzo, Srinivasan Yegnasubramanian, Laura DeLong Wood, Laura A. Sena, Rachel Karchin

SVCFit estimates SV cellular fractions from bulk sequencing to reconstruct clonal evolution in mCRPC under therapy, showing treatment-driven clonal reconfiguration.

bioRxiv · Feb 1, 2025 · PreprintBioinformatics