Author

Laurent Jacob

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Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Etienne Rajon· 1 shared Frédéric Menu· 1 shared Salomé BourgiD· 1 shared Terence P Speed· 1 shared

Activity by Year

2016-2018 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 3 mutual co-author links

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1 shared paperEvolutionary Biology

Etienne Rajon

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2 papers

Recent·Most cited

How evolution draws trade-offs

Salomé Bourg, Laurent Jacob, Frédéric Menu, Etienne Rajon

This paper models how trade-off shapes evolve through genetic drift and selection, showing their curvature and length depend on resource costs and ecological context.

bioRxiv · Feb 28, 2018 · PreprintEvolutionary Biology

The healthy ageing gene expression signature for Alzheimer’s disease diagnosis: a random sampling perspective

Laurent Jacob, Terence P Speed

The paper reproduces an Alzheimer's disease gene expression diagnosis method and shows its performance is not better than random sampling of similar-sized probe-sets.

bioRxiv · Apr 5, 2016Bioinformatics