ST6Gal2 promotes α2,6-sialylation and aggressive phenotypes in neuroblastoma cells
Laxmi Swami, Punarvi Mandadapu, Mayra E Lopez, Sarah K Vaughan, Abigail R Richardson, Pracheta Janmeda, Karin M. Hardiman, Laura L. Stafman
This study shows that ST6Gal2 promotes aggressive neuroblastoma traits by enhancing 2,6-sialylation, linking its expression to poor clinical outcomes and mesenchymal transcriptional signatures.
bioRxiv · Sep 28, 2026 · PreprintCancer Biology