Cross-modality representation and multi-sample integration of spatially resolved omics data
Zhen Li, Xuejian Cui, Xiaoyang Chen, Zijing Gao, Yuyao Liu, Yan Pan, Shengquan Chen, Hairong Lv, Lei Zhai, Rui Jiang
This paper introduces PRESENT, a contrastive learning framework for integrating spatially resolved multi-omics data across samples and modalities, showing improved performance in detecting spatially functional domains and biological regulatory mechanisms.
Briefings in Bioinformatics · Apr 25, 2026Peer-reviewedBioinformatics