Single-Cell and Spatial Profiling of Tumor Microenvironment Heterogeneity in Human Osteosarcomas
Xuejing Zheng, Jinbo Yuan, Jin Peng, Xuejun Wang, Runlei Xu, Helin Feng, Liangliang Wu, Yongjie Xie, Xinxin Zhang, Wence Wu
This study uses single-cell and spatial transcriptomics to analyze tumor microenvironment heterogeneity in osteosarcomas, identifying distinct cellular states and spatial niches.
bioRxiv · Jun 27, 2025 · PreprintCancer Biology