Retrospective varying coefficient association analysis of longitudinal binary traits: application to the identification of genetic loci associated with hypertension
Gang Xu, Amei Amei, Weimiao Wu, Yunqing Liu, Linchuan Shen, Edwin C. T. Oh, Zuoheng Wang
This study introduces RVMMAT, a method for detecting time-varying genetic effects on longitudinal binary traits, and applies it to identify hypertension-associated loci.
The Annals of Applied Statistics · Jan 31, 2024Peer-reviewedGenetics