SigBridgeR: An Integrative Framework and Toolkit for Comprehensive Screening and Benchmarking of Phenotype-Associated Cell Subpopulations in Single-Cell Transcriptomics
Yuxi Yang, Zeyu Yan, Hongqian Qian, Chunyang Wang, Liping Du, Y Peng, Xiaoyun Bu, Jian‐Guo Zhou, Shixiang Wang
SigBridgeR benchmarks phenotype-associated cell subpopulations across four cancer types using eight algorithms, providing standardized workflows and visualization tools for reproducible analysis.
bioRxiv · May 12, 2026 · PreprintBioinformatics