Hookworm genomic diversity and population structure from accessible sample types: A validated approach to generate genome-wide polymorphism datasets from individual third-stage larvae
Kaylee S. Herzog, Savanna S. Randi, Dickson Osabutey, Christina L. Paraggio, Richard D. Bungiro, Lisa Harrison, Irene Owusu Donkor, Francis Appiah-Twum, Amanda N. L. Lamptey, Isaac Quaye, Shaelynn Vaughan, Michael D. Wilson, Anita Ghansah, Michael Cappello, Joseph R. Fauver
The paper validates a method to generate genome-wide polymorphism datasets from individual hookworm larvae, showing that accurate variant calling is possible with sufficient DNA input and strict filtering.
bioRxiv · Feb 20, 2026 · PreprintGenomics