High-Activity Enhancer Generation based onFeedback GAN with Domain Constraint andCurriculum Learning
Jia-Hao Li, Liwei Xiao, Jiawei Luo, Xianliang Liu, Junjie Chen
This paper introduces Enhancer-GAN, a GAN-based method for generating high-activity enhancer sequences, showing improved activity compared to benchmark datasets and identifying new motifs.
IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · Dec 5, 2023Peer-reviewedBioinformatics