Basal p53 maintains a distinct transcriptional program from irradiated p53 in tissue, including tumor suppressors
Royce W. Zhou, James J. Manfredi, Lois Silverman, Ramon E. Parsons
This study defines the murine basal p53 epigenome and transcriptional program in normal tissues, showing it regulates tumor suppressors distinct from the DNA damage response.
bioRxiv · Jul 11, 2024 · PreprintBiochemistry