Single-cell transcriptomics reveals diverse and complex gene expression alterations in human trisomy 18
Jing Wang, Zixi Chen, Fei He, Trevor Lee, Wenjie Cai, Wanhua Chen, Longbin Zhang, Nan Miao, Zhiwei Zeng, Ghulam Hussain, Qiwei Guo, Tao Sun
This study uses single-cell transcriptomics to analyze gene expression changes in trisomy 18 samples, identifying altered cell groups and new critical regions associated with the syndrome.
bioRxiv · Dec 3, 2019 · PreprintGenetics