Non-invasive characterization of human bone marrow by cell free messenger-RNA reveals response to growth factor stimulation and hematopoietic reconstitution after transplantation
Arkaitz Ibarra, Jiali Zhuang, Yue Zhao, Neeraj S. Salathia, Vera Huang, Alexander D. Acosta, Jonathan Aballi, Shusuke Toden, Amy P. Karns, Intan Purnajo, Julianna R. Parks, Lucy Guo, James R. Mason, Darren S. Sigal, Tina S. Nova, , Michael I. Nerenberg
This study shows that cell-free mRNA reflects BM transcriptional activity and functional changes in response to growth factors and hematopoietic reconstitution.
Nature Communications · Jan 21, 2020Peer-reviewedMolecular Biology