A Statistical Framework to Infer the Mutation Model of Tandem Repeat Variants
Luis G Fernandez Luna, Sebastián Iturbe, Carolina de Lima Adam, Nathaniel S. Pope, Diego Ortega‐Del Vecchyo, Rori V. Rohlfs
This paper introduces TRAMA, a method to estimate mutation models for tandem repeats using ancestral recombination graphs, showing accurate parameter estimation under SMM and TPM.
bioRxiv · Jan 24, 2026 · PreprintEvolutionary Biology