PALM3 and hearing loss: a potential dual diagnosis interfering with novel gene discovery
Paria Najarzadeh Torbati, Lukas Hallbrucker, Michaela A. H. Hofrichter, Daniel Owrang, Jonas Setzke, Manfred W. Kilimann, Anahid Hemmatpour, Mohsen Rajati, Ehsan Ghayoor Karimiani, Thomas Haaf, Christian Vogl, Barbara Vona
The paper identifies a homozygous splice-site variant in PALM3 and a missense variant in OTOA in a family with autosomal recessive hearing loss, supporting PALM3 as a candidate gene through functional and comparative analysis.
European Journal of Human Genetics · Jul 29, 2026Peer-reviewedGenetic & Genomic Medicine