Genetic Profiling and Early Detection of Type 2 Diabetes Subtypes through Sex-Stratified GWAS and Explainable AI
Lorena Alonso, Miguel Ángel Pérez, Mohammed Yousef Salem Ali, Maedeh Mashhadikhan, Nicolás Gaitán, Leila Satari, Rodrigo Martín, Anthony Piron, Xavier Farré, Natàlia Blay, Lydia Ruiz, Aikaterini Lymperidou, Cecilia Salvoro, Rafael de Cid, Josep Ll. Berral, , David Torrents
This study uses sex-stratified GWAS and explainable AI to identify 184 genes associated with T2D subtypes and improve risk detection.
medRxiv · Jul 24, 2025 · PreprintGenetic & Genomic Medicine