Analysis of patient derived xenograft studies in Oncology drug development: impact on design and interpretation of future studies
J. Dickinson, M. de Matas, P. Dickinson, H. Mistry
This paper compares model-based analysis and un-paired t-test for PDX xenograft studies, finding model-based methods more powerful and capable of detecting smaller treatment effects.
bioRxiv · Mar 15, 2019 · PreprintCancer Biology