RNA sequencing and lipidomic analysis of alveolar macrophages from normal and CD44 deficient mice
Y. Dong, A. A. Arif, J. Guo, Z. Ha, S. S. M. Lee-Sayer, G. F. T. Poon, M. Dosanjh, C. D. Roskelley, T. Huan, P. Johnson
This study shows CD44 deficiency in mice leads to impaired alveolar macrophage lipid homeostasis, increased surfactant lipids, and exacerbated lung inflammation.
bioRxiv · Nov 17, 2019Immunology