Targeted DNA Sequencing of Cutaneous Melanoma Identifies Prognostic and Predictive Alterations
H. Vasudevan, A. M. Haugh, R. C. Osorio, R. A. Francois, M. E. Tawil, K. K. Tsai, M. Tetzlaff, A. Daud
This study identifies prognostic and predictive alterations in cutaneous melanoma using targeted DNA sequencing and clinical follow-up, finding NRAS mutations correlate with worse survival and elevated TMB with better progression-free survival on combination ICI.
bioRxiv · Jan 18, 2024Cancer Biology