Phosphorylation of serines 287/288 in DEK regulates cell-type-specific chromatin occupancy and compaction
Gongjie Wu, M. F. Meister, Sandra Reissner, Pia J Mueller, Ferdinand Kappes
This study shows that phosphorylation of DEK at S287/S288 by CK2 regulates its chromatin binding and transcriptional activity in a cell-type-specific manner, affecting chromatin compaction and oncogenic pathways in melanoma.
bioRxiv · Jan 20, 2026 · PreprintBiochemistry