High-Throughput Single-Molecule Analysis via Divisive Segmentation and Clustering
D. White, M. Goldschen-Ohm, R. Goldsmith, B. Chanda
The paper introduces DISC, a platform that accelerates single-molecule trajectory analysis with divisive clustering, revealing a lack of cooperativity in HCN channel domains.
bioRxiv · Apr 9, 2019Biophysics