Structural Insights on Ionizable Dlin-MC3-DMA Lipids in DOPC Layers by Combining Accurate Atomistic Force Fields, Molecular Dynamics Simulations and Neutron Reflectivity
M. Ibrahim, J. Gilbert, M. Heinz, T. Nylander, N. Schwierz
This study develops and validates force field parameters for MC3 lipids using molecular dynamics and neutron reflectivity experiments to better model lipid nanoparticle structures.
bioRxiv · Feb 28, 2023Biophysics