Molecular Dynamics simulation of TDP-43 RRM in the presence and absence of RNA
D. Scott, D. Mowrey, K. Nagarajan, L. Francois-Moutal, A. Nair, M. Khanna
This study uses molecular dynamics simulations to analyze TDP-43 RRM domains in the absence of RNA and compares them to RNA-bound structures to identify potential druggable sites.
bioRxiv · Mar 15, 2022 · PreprintBiophysics