Transcriptome responses to reduced dopamine in the Substantia Nigra Pars Compacta reveals a potential protective role for dopamine.
M. Koltun, Karol Cichewicz, Jeffrey T. Gibbs, Martin Darvas, Jay Hirsh
The paper uses a genetic model to study transcriptome changes in dopamine-depleted mice, finding DA-dependent gene expression in SNc that suggests a protective role for dopamine.
bioRxiv · Sep 9, 2019 · PreprintNeuroscience