Sex-dependent transcriptional control of cardiac electrophysiology by histone acetylation modifiers based on the GTEx database
M. P. Pressler, A. Horvath, E. Entcheva
The paper uses GTEx data to show sex-specific effects of histone modifiers on cardiac ion channels via transcription factors, with male models underestimating female effects.
bioRxiv · Apr 19, 2022Bioengineering