Author

M. R. Mughal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. Siepel· 1 shared M. DeGiorgio· 1 shared N. E. Dukler· 1 shared R. Ramani· 1 shared Y.-F. Huang· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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1 shared paperEvolutionary Biology

A. Siepel

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2 papers

Recent·Most cited

Extreme purifying selection against point mutations in the human genome

N. E. Dukler, M. R. Mughal, R. Ramani, Y.-F. Huang, A. Siepel

The paper introduces ExtRaINSIGHT to measure purifying selection in the human genome using whole genome sequences, finding ultraselection in specific regions and estimating lethal mutation rates.

bioRxiv · Aug 23, 2021Evolutionary Biology

Localizing and classifying adaptive targets with trend filtered regression

M. R. Mughal, M. DeGiorgio

This paper introduces Trendsetter, a method for detecting and classifying genomic regions under natural selection, showing it is robust to missing data and background selection.

bioRxiv · Sep 5, 2018Evolutionary Biology