Extracellular communication between brain cells through functional transfer of Cre mRNA
D. Rufino-Ramos, K. Leandro, P. Perdigao, K. O'Brien, M. Pinto, M. Santana, T. SOLINGE, S. Mahjoum, X. Breakefield, K. Breyne, L. Pereira de Almeida
The paper develops a method to track brain-derived extracellular vesicles (bdEVs) by using Cre mRNA and a reporter system, showing their functional transfer across the brain and bloodstream.
bioRxiv · Jan 29, 2023 · PreprintCell Biology