Single cell analysis of the effects of developmental lead (Pb) exposure on the hippocampus.
J. A. Colacino, J. Dou, R. Thompson, C. T.-Y. Lee, L. Y. Middleton, P. P. U. Bambarendage, S. P. Ferris, T. R. Jones, K. Neier, X. Zhou, M. Sartor, S. S. Hammoud, D. C. Dolinoy, K. M. Bakulski
This study uses single-cell RNA sequencing to analyze how perinatal lead exposure affects hippocampal cell types in mice, finding increased oligodendrocytes and altered gene expression in specific cell clusters.
bioRxiv · Nov 29, 2019 · PreprintPharmacology & Toxicology