Revisiting the interaction of heme with hemopexin: Recommendations for the responsible use of an emerging drug
M. S. Detzel, B. F. Syllwasschy, F. Steinbock, A. Ramoji, M.-T. Hopp, A. A. Paul George, U. Neugebauer, D. Imhof
This study revisits the heme-binding affinity and ratio of hemopexin, finding a lower affinity and potential 2:1 binding ratio, with implications for its therapeutic use in hemolytic disorders.
bioRxiv · Apr 16, 2020 · PreprintBiochemistry