A convolutional neural network highlights mutations relevant to antimicrobial resistance in Mycobacterium tuberculosis
Anna G. Green, Chang Ho Yoon, Michael L. Chen, Yasha Ektefaie, Mack Fina, Luca Freschi, Matthias I. Gröschel, Isaac S. Kohane, Andrew L. Beam, Maha Reda Farhat
This paper presents a deep convolutional neural network to predict antibiotic resistance in M. tuberculosis isolates, achieving state-of-the-art accuracy and enabling interpretable feature analysis.
Nature Communications · Jul 2, 2022Peer-reviewedGenomics