Auditing Confidence-Calibrated Benchmarking of Single-Cell Perturbation Models
Manuel Gallone, Shyam Ravidath, Srihith Madireddy
The paper audits a benchmarking framework for single-cell perturbation models, revealing flaws in metric interpretation and calibration, and identifies a specific calibration failure in split-conformal prediction.
bioRxiv · Oct 19, 2026 · PreprintBioinformatics