Author

Manuel Irimia

Primary ORCID profile (0000-0002-2179-2567 · 31 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Manuel IrimiaiD31 papers · Institució Catalana de Recerca i Estudis Avançats

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

Benjamin J. Blencowe· 2 shared Carolyn L. CumminsiD· 1 shared ChangJiang Xu· 1 shared Daniel H. Geschwind· 1 shared Debashish RayiD· 1 shared Emma Zilberman· 1 shared Gary D. BaderiD· 1 shared Henry Krause· 1 shared

Activity by Year

2016-2016 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Benjamin J. Blencowe

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2 papers

Recent·Most cited

Global changes in patterning, splicing and primate specific lncRNAs in autism brain

Neelroop N. Parikshak, Vivek Swarup, T. Grant Belgard, Michael Gandal, Manuel Irimia, Virpi Leppa, Jennifer K. Lowe, Robert Johnson, Benjamin J. Blencowe, Steve Horvath, Daniel H. Geschwind

This study identifies convergent transcriptomic changes in ASD brains, including noncoding RNA and splicing alterations, and links them to genetic risk factors and biological pathways.

bioRxiv · Sep 25, 2016 · Preprint

ARGLU1 is a Glucocorticoid Receptor Coactivator and Splicing Modulator Important in Stress Hormone Signaling and Brain Development

Lilia Magomedova, Jens Tiefenbach, Emma Zilberman, Veronique Voisin, Melanie Robitaille, Serge Gueroussov, Manuel Irimia, Debashish Ray, Rucha Patel, ChangJiang Xu, Pancharatnam Jeyasuria, Gary D. Bader, Timothy R. Hughes, Henry Krause, Benjamin J. Blencowe, , Carolyn L. Cummins

This study identifies ARGLU1 as a glucocorticoid receptor coactivator and splicing modulator, showing its role in stress hormone signaling and brain development through genetic and transcriptomic analyses.

bioRxiv · Aug 12, 2016Molecular Biology