Author

María Ortiz

Bristol-Myers Squibb (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:deconvolution· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Asier AntoranziD· 2 shared Jon Pey· 2 shared Carlos MackintoshiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersBioinformatics

Asier AntoranzORCID

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2 papers

Recent·Most cited

ELITE: Expression deconvoLution using lInear optimizaTion in bulk transcriptomics mixturEs

Asier Antoranz, Carlos Mackintosh, María Ortiz, Jon Pey

ELITE deconvolves bulk transcriptomic data using linear programming to estimate cell type composition, outperforming existing methods in cases with similar expression profiles.

bioRxiv · Mar 6, 2023 · PreprintBioinformatics

ELIMINATOR: Essentiality anaLysIs using MultIsystem Networks And inTeger prOgRamming

Asier Antoranz, María Ortiz, Jon Pey

The paper introduces an in-silico method to identify patient-specific essential genes using constraint-based modeling and validates it against experimental data from cancer cell lines.

BMC Bioinformatics · Aug 6, 2022Peer-reviewedBioinformatics