Author

Margherita Tonini

École Polytechnique Fédérale de Lausanne

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

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David Liaskos· 1 shared María MasidiD· 1 shared Omid OftadehiD· 1 shared Vassily Hatzimanikatis AiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperSystems Biology

David Liaskos

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1 paper

Recent·Most cited

Mechanistic reconstruction of receptor-to-transcription factor signaling integrating prior knowledge and omics

David Liaskos, Omid Oftadeh, Margherita Tonini, María Masid, Vassily Hatzimanikatis A

The paper introduces SIGMA, a framework that reconstructs receptor-to-transcription factor signaling by integrating prior knowledge and omics data to uncover metabolic reprogramming mechanisms.

bioRxiv · Jun 22, 2026 · PreprintSystems Biology