Brain and Organoid Manifold Alignment (BOMA), a machine learning framework for comparative gene expression analysis across brains and organoids
Chenfeng He, Noah Cohen Kalafut, Soraya O. Sandoval, Ryan D. Risgaard, Chen Yang, Saniya Khullar, Marin Suzuki, Qiang Chang, Xinyu Zhao, André M. M. Sousa, Daifeng Wang
BOMA identifies conserved and specific developmental gene expression programs between human brains and organoids at cellular resolution.
bioRxiv · Jun 13, 2022 · PreprintBioinformatics