Widely dispersed clonal expansion of multi-fungicide-resistant Aspergillus fumigatus limits genomic epidemiology prospects
Eveline Snelders, Brandi N. Celia-Sanchez, Ymke C. Nederlof, Jianhua Zhang, Hylke H. Kortenbosch, Bas J. Zwaan, Marlou C. Tehupeiory-Kooreman, Alejandra Giraldo-López, Karin van Dijk, Li Wang, Marin T. Brewer, Michelle Momany, Ben Auxier, Paul E. Verweij
This study links triazole-resistant A. fumigatus isolates from environmental hotspots to clinical cases of aspergillosis, showing widespread clonal expansion that limits genomic epidemiology's ability to trace infection sources.
mBio · May 20, 2025Peer-reviewedMicrobiology