A scalable method for estimating the regional polygenicity of complex traits
Ruth Johnson, Kathryn S. Burch, Kangcheng Hou, Mario Paciuc, Bogdan Paşaniuc, Sriram Sankararaman
This paper introduces BEAVR, a scalable method to estimate regional polygenicity using GWAS effect sizes and LD information, showing it provides unbiased estimates compared to existing methods.
Lecture notes in computer science · Jan 1, 2020Peer-reviewedGenetics